Contact Information

• Office: Room 1335, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology

• Email: taolm@ecust.edu.cn

• Office Phone: 021-64253756

• Office Fax: 021-59883730

Education

• 2005.12  Ph.D.  Doctor of Science, Chinese Academy of SciencesShanghai Institutes, Shanghai, P. R. China

• 1987.07  M.Sc.  Agronomy degree, Chinese Academy of Agricultural Sciences, Shanghai, P. R. China

• 1982.07  B.S.  Bachelor of engineering, original name Donghua University of Chemical Technology (East China University of Science and Technology), Shanghai, P. R. China

Group Members

Researchers:

Sen. Eng. Wenping Xu, Dr. Yang Zhang,

Mr. Liang Cheng, Mr. Youwu Hao, Ms. Yun Yang, Mr. Yuanseng Chang, Mr. Hui Chen, Mr. Lei Ding, Ms. Ping Zhang, Ms. Yangyang Fan, Ms. Yutian Liu, Mr. Hongfei Ni, Mr.Wengtao Chen, Ms. Nan Zhang, Ms. Yandi Li, Ms. Shuang Han, Ms. Susu Wang

Research Interests

Firstly: Biological pesticide development

Explore, research and creation about agricultural antibiotic of natural products

Secondly: Pesticide toxicology

Systematic research the mode, mechanism and metabolism of action of pesticides, focused on the potential target of pesticides and its effects on non-target organisms and environmental ecology.

Professional experience

2010-now     East China University of Science and Technology (ECUST)

1987-2010     Shanghai Pesticide Research Institute

1996-1997     Agricultural of bioactive substance BASF of Germany

1991-1992     Agricultural of bioactive substance in RIKEN of Japan

1982-1984     Wuhan Institute of Hydrobiology, Chinese Academy of Science

Publication from 2010 in ECUST:

1. Yun Yang, Jufang Gao, Yang Zhang, Wenping Xu, Youwu Hao, Zhiping Xu, Liming Tao*.,Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway. Environmental Pollution, 2018, 241:1091-1097.

2. Yun Yang, Wenjing Liu, Jian Wang, Yang Zhang, Wenping Xu, Liming Tao*.,The different effects of natural pyrethrins and beta -cypermethrin on human hepatocyte QSG7701 cells by ROS-mediated oxidative damage. Environmental Science & Pollution Research International (2018),https://doi.org/10.1007/s11356-018-2503-3.

3. Yang Zhang, Yuansen Chang, Haijing Cao, Wenping Xu, Zhong Li, Liming Tao*., Potential threat of Chlorpyrifos to human liver cells via the caspase-dependent mitochondrial pathways. Food & Agricultural Immunology,2018, 29:294-305.

4. Wenping Xu, Songlin Liu, Yang Zhang, Jufang Gao, Mingjun Yang, Xiao  Liu, Liming Tao*., Cypermethrin resistance conferred by increased target insensitivity and metabolic detoxification in Culex pipiens pallens Coq. Pesticide Biochemistry and Physiology, 2017, 142:77.

5. Yang Zhang, Jigang Wu, Wenping Xu, Jufang Gao, Haijing Cao, Mingjun  Yang, Bo Wang, Youwu Hao, Liming Tao*., Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays. Environmental Pollution, 2017, 220(Pt B):1127-1137.

6. Yun Yang, Mimi Zong, Wenping Xu, Yang  Zhang, Bo Wang, Mingjun Yang,  Liming Tao*., Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway. Chemico-Biological Interactions, 2017, 262:38-45.

7. Wenping Xu, Bo Wang, Mingjun Yang, Yang Zhang, Zhiping Xu, Yun Yang,  Haijing Cao, Liming Tao*., Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environmental Toxicology and Pharmacology, 2017, 49:89 - 96.

8. Youwu Hao, Gaohui Zhou, Wei Wu, Yang Zhang, Liming  Tao, Jianhua Yao, Wenping Xu*., Synthesis and antiviral evaluation of novel N-6 substituted adenosine analogues. Tetrahedron Letters, 2017, 58(3):190-193.

9. Mingjun Yang, Bo Wang, Jufang Gao, Yang Zhang, Wenping Xu,  Liming Tao*., Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome c release in spodoptera frugiperda Sf9 cells. Chemosphere, 2017, 169:155-161.

10. Mingjun Yang, Guanggang Xiang, Diqiu Li, Yang Zhang, Wenping Xu,  Liming Tao*., The insecticide spinosad induces DNA damage and apoptosis in HEK293 and HepG2 cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2016, 812:12-19.

11. Yang Zhang, Mingming Luo, Wenping Xu, Mingjun Yang, Bo Wang, Jufang  Gao, Yaxiao Li, and Liming Tao*., Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis. Journal of Agricultural and Food Chemistry, 2016, 64(36): 6895-6902.

12. Zhiping Xu, Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang  Zhang, Yun Yang, Liming Tao*., Pyrethrum-extract induced autophagy in Insect cells: A new target? Pesticide Biochemistry and Physiology, 2016, 137:21-26

13. Xiaoqin Yu, Yang Zhang, Mingjun Yang, Junfu Guo, Wenping Xu, Jufang  Gao, Yaxiao Li, Liming Tao*., Cytotoxic effects of tebufenozide in vitro bioassays. Ecotoxicology and Environmental Safety, 2016, 129: 180-188.

14. Yang Zhang, Songlin Liu, Xing Yang, Mingjun Yang, Wenping Xu, Yaxiao  Li, Liming Tao*., Staurosporine shows insecticidal activity  against Mythimna separata．Pesticide Biochemistry and Physiology, 2016, 128: 37-44.

15. Xiwei Wu, Lei Zhang, Chao Yang, Mimi Zong, Qingchun Huang*,  Liming Tao., Detection on emamectin benzoate induced apoptosis and DNA damage in  Spodoptera rugiperda Sf9 cell line.  Pesticide Biochemistry and Physiology, 2016, 126: 6–12.

16. Diqiu Li, Qingchun Huang*,  Miaoqing Lu, Lei Zhang, Zhichuan Yang, Mimi Zong, Liming  Tao*., The organophosphate insecticide chlorpyrifos confers its genotoxic effects by inducing DNA damage and cell apoptosis.  Chemosphere，2015, 135: 387–393.

17. Diqiu Li, Xiwei Wu, Xiaoqin Yu, Qingchun Huang, Liming  Tao*., Synergistic effect of nonionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides. Environmental Toxicology and Pharmacology, 2015, 39: 677–682.

18. Qingchun Huang*, Xiwei Wu, Xiaoqin Yu, Lei Zhang, Miaoqing Lu,  Liming Tao*., Comparison of the cytotoxic impact of chlorfluazuron on selected insect and human cell lines.  Environmental Toxicology Chemical, 2015, 34(7): 1675-1682.

19. Wenping Xu, Qingchun Huang*, Xiwei Wu, Xiaoqin Yu, Xuexiao  Wang, Liming Tao. Property of midgut a-amylase from Mythimna separate (Lepidoptera: Noctuidae) larvae and its responses to potential inhibitors in vitro. Journal of Insect Science, 2014, 14(1).

20. Xiuyuan Zhuang, Daojing Zhang, Wen Qin, Jia Deng, Hui Shan,  Liming Tao* and Yuanguang Li*., A comparison on the preparation of hot water extracts from Chlorella pyrenoidosa (CPEs) and radical scavenging and macrophage activation effects of CPEs. Food & Function,2014, 5(12):3252-3260.

21. Xiang Guanggang, Li Diqiu, Yuan Jianzhong, Guan Jingmin, Zhai  Huifeng, Shi Mingan*, Tao Liming*., Carbamate insecticide methomyl confers cytotoxicity through DNA damage induction.  Food and Chemical Toxicology,2013, 53,352-358.

22. Wenping Xu, Daojing Zhang, Congcong Si, Liming  Tao*., ANTIFUNGAL MACROLIDES FROM Streptomyces cavourensis YY01-17. Chemistry of Natural Compounds, 2013, 49(5), 988-989.

23. Daojing Zhang, Gang Wei, Ying Wang, Congcong Si, Li Tian,  Li-ming Tao* and Yuan-guang Li. Bafilomycin K, a new antifungal macrolide from Streptomyces flavotricini Y12-26. The Journal of Antibiotics, 2011, 64, 391–393.

24. Baoju Li, Huizhu Yuan, Jichao Fang, Liming  Tao, Qingchun Huang*, Xuhong Qian*, Zhijin Fan. Recent progress of highly efficient in vivo biological screening for novel agrochemicals in China. Pest Management Science,2010, 66 (3): 229 – 344

25. Dao-Jing Zhang, Rong-Feng Liu, Yuan-Guang Li*, Li-Ming  Tao, Li Tian. Two New Antifungal Cyclic Lipopeptides from Bacillus marinus B-9987. Chemical & Pharmaceutical Bulletin, 2010, 58(12):1630-1634

26. Rong-Feng Liu, Dao-Jing Zhang, Yuan-Guang Li*, Li-Ming  Tao, Li Tian*. A New Antifungal Cyclic Lipopeptides from Bacillus marinus B-9987. Helvetica Chimica Acta, 2010, 93 (12): 2419-2425.