Contact Information

• Office:Room 433, Researching Building 18

• Email: jinz@ecust.edu.cn

• Office Phone: +86 21 64252584

• Office Fax: +86 21 64252584

Education

• 03/2007-06/2009  M.D.  Medicinal Chemistry, East China University of Science & Technology, Shanghai, China

• 09/2000-07/2003  M.S.  Medicinal Chemistry, Shenyang Pharmaceutical University, Shenyang, China

• 09/1996-07/2000  B.E.  Medicinal Chemistry, Shenyang Pharmaceutical University, Shenyang, China

Professional Experience

• 09/2014-now  Associate Professor, School of Pharmacy, East China University of Science & Technology, Shanghai, China

• 06/2009-09/2014  Lecturer, School of Pharmacy, East China University of Science & Technology, Shanghai, China

• 07/2003-12/2006  Lecturer, School of Pharmacy, Huazhong University of Science & Technology, Wuhan, China

Research Interests

• Enantioselective Organocatalytic synthesis of natural products and therapeutics

• Development of novel antimalarial agents for resolving the ever-increasing drug-resistance of plasmodium

Publication

1. Shuaishuai Ni^#, Baoli Li^#, Feifei Chen^#, Hanwen Wei, Fei Mao, Yifu Liu, Yixiang Xu, Xiaoxia Qiu, Xiaokang Li, Wenwen Liu, Linghao Hu, Dazheng Ling, Manjiong Wang, Xinyu Zheng, Jin Zhu*, Lefu Lan*, Jian Li*. Novel staphyloxanthin inhibitors with improved potency against multidrug resistant Staphylococcus aureus. ACS Med. Chem. Lett. 2018, 9, 233–237.

2. Wenhua Chen^#, Xue Yao^#, Zhenghui Huang^#, Fei Mao, Longfei Guan, Yun Tang, Hualiang Jiang, Jian Li, Jin Huang*, Lubin Jiang*, Jin Zhu*. Novel dual inhibitors against FP-2 and PfDHFR as potential antimalarial agents: Design, synthesis and biological evaluation. Chin. Chem. Lett. 2018, doi:10.1016/j.cclet.2017.11.041

3. Wenhua Chen^#, Zhenghui Huang^#, Wanyan Wang^#, Fei Mao, Longfei Guan, Yun Tang, Hualiang Jiang, Jian Li, Jin Huang*, Lubin Jiang*, Jin Zhu*. Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely. Bioorg. Med. Chem. 2017, 25, 6467–6478.

4. Deyan Wu, Xuwen Zhang, Yong Xu, Yingfei Xue, Jian Li, Wei Wang*, Jin Zhu*. Organocatalytic enantioselective Friedel–Crafts reaction of 1-naphthols with isatins and an unexpected spontaneous dehydration process. Asian J. Org. Chem. 2014, 3, 480–486.

5. Tengfei Li, Jin Zhu, Deyan Wu, Xiangmin Li, Sinan Wang, Hao Li, Jian Li*, Wei Wang*.A strategy enabling enantioselective direct conjugate addition of inert aryl methane nucleophiles to enals with a chiral amine catalyst under mild conditions. Chem.- Eur. J. 2013, 19, 9147–9150.

6. Maosheng Lv^#, Ting Shi^#, Xiaona Mao^#, Xi Li, Yingyi Chen, Jin Zhu*, Shuaishuai Ni, Xu Shen, Hualiang Jiang, Jian Li, Jian Zhang*, Jin Huang*. 1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: A novel cyclophilin A allosteric activator. Biochem. Biophys. Res. Commun. 2012, 425, 938−943.

7. Jin Zhu, Shunting Yu*, Wenchao Lu, Jing Deng, Jian Li, Wei Wang*. Direct oxidative conversion of 3-aryl propionaldehydes to 3-aryl acroleins promoted by SOMO catalysis. Tetrahedron Lett. 2012, 53, 1207–1209.

8. Jin Zhu, Jie Liu, Ruoqun Ma, Hexin Xie, Jian Li*, Hualiang Jiang, Wei Wang*. A direct amine-Pd(OAc)₂ co-catalyzed Saegusa oxidation reaction of unmodified aldehydes to α, β-unsaturated aldehydes. Adv. Synth. Catal. 2009, 351, 1229–1232.