Contact Information

• Office:Room  910, Researching Building 18

• Email: chuch@ecust.edu.cn

• Office Phone: +86 21 6425 0627

• Office Fax: +86 21 6425 0627

Education

• 2000.06 Ph.D.Organic Chemistry, Lanzhou University, Lanzhou, P. R. China

• 1995.06  BachelorApplied Chemistry, Lanzhou University, Lanzhou, P. R. China

Professional Experience

• 2007-now School of pharmacy, East China University of Science & Technology, Shanghai, P. R. China

• 2004-2006 Nagoya University, Japan, Postdoctoral Researcher.

• 2002-2004  Kobe University, Japan, Postdoctoral Researcher.

• 2002-2002  Dalian Institute of Chemical Physics, Chinese Academy.

• 2000-2001 Dalian Institute of Chemical Physics, Chinese Academy, Postdoctoral Researcher.

Research Interests

• API Organic process development

• Organic synthetic methodology

• Heterogenous catalyst development

Publication

1. Zhu C., Li H., Chu C. *, Direct C(sp3)-H functionalization of 2-methylazaarenes using 4-substituted-TEMPO. Tetrahedron Letters., 59, 4454-4457, 2018.

2. Li Y., Sheng Z., Zhu C., Yin W., Chu C. *, Silica based click-dibenzo-18-crown-6-ether high performance liquid chromatography stationary phase and its application in separation of Fullerenes. Talanta, 178, 195-201, 2018.

3. Zhu C., Guo R., Sheng Z., Li Y. and Chu C.*, A facile synthesis of benzo[h]quinolines via silica-TsOH-P2O5 promoted condensation of 1-naphthylamines with 1,3-diketones under solvent free conditions. Chin. J. Chem., 35(10), 1595-1600, 2017.

4. 盛 哲, 马 明, 彭玲玲, 张志坤, 褚长虎*, 张 艳, 王剑波*,铜催化的立体选择性Doyle-Kirmse 反应, Chin. J. Org. Chem., 37, 1730～1740, 2017.

5. Sheng Z., Zhang Z., Chu C., Zhang Y., Wang J.,  Transition metal-catalyzed [2,3]-sigmatropic rearrangements of ylides: An update of the most recent advances, Tetrahedron 73, 4011-4022, 2017.

6. Yin W., Cheng L., Chai H., Guo R., Liu R., Chu C. *, Palasota John A., and Cai X., Silica-Based 2-(N,N-dimethylamino)-1,3-propanediol Hydrophilic Interaction Liquid Chromatography Stationary Phase for Separating Cephalosporins and Carbapenems, Anal Bioanal Chem., 407, 6217-6220, 2015.

7. Guo R., Zhu C., Sheng Z., Li Y., Yin W., and Chu C. *, Silica Sulfuric Acid Mediated Acylation of Amines with 1,3-Diketones via C-C Bond Cleavage under Solvent-free Conditions, Tetrahedron Letters., 56, 6223-6226, 2015.

8. Yin W., Chai H., Liu R., Chu C.*, Palasota J., Cai X., Click N-benzyl iminodiacetic acid: Novel silica-based tridentate zwitterionic stationary phase for hydrophilic interaction liquid chromatography, Talanta, 132, 137-145, 2015.

9. Chai H.,  Guo R., Yin W., Cheng L., Liu R., Chu C.*, One-Pot, Three-Component Reaction Using Modified Julia Reagents: A Facile Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles in a Wet Organic Solvent, ACS Comb. Sci., 17(3), 147-151, 2015.

10. Shen J., Sun J., Qin S., Chu C., Liu  R., 4-Benzamido-TEMPO Catalyzed Oxidation of a Broad Range of Alcohols to the Carbonyl Compounds with NaBrO3 under Mild Conditions, Chin. J. Chem., 32(5), 405-409, 2014.

11. Shen J., Yang D., Liu Y., Qin S., Zhang J., Sun J., Liu C., Liu C., Zhao X., Chu C., Liu R., Copper-Catalyzed Aerobic Oxidative Coupling of Aromatic Alcohols and Acetonitrile to beta-Ketonitriles, Org. Lett., 16(2), 350-353. 2014.

12. Yang J., Yin W., Liu R., Chu C.*, Ti(Oi-Pr)4 Mediated Olefination between Julia Reagent and Aldehydes under Mild Conditions: Facile Synthesis of Vinyl Sulfones, J. Chin. Chem. Soc., 60( 4), 412-417, 2013.

13. Jin X., Liu Y., Lu Q., Yang D., Sun J., Qin S., Zhang J., Shen J., Chu C., Liu R., Formation of C=N bonds by the release of H2: a new strategy for synthesis of imines and benzazoles, Org. Biomol. Chem., 11(23), 3776-3780, 2013.

14. Shen G. , Zhang F. , Yang B., Chu C. , Liang X., A novel amide stationary phase for hydrophilic interaction liquid chromatography and ion chromatography, Talanta,  115, 129-132, 2013.

15. Yang J., Yin W., Liu R. and Chu C.*, Facile synthesis of 4,5-disubstituted 2H-1,2,3-triazoles by catalyst-free cycloaddition between substituted vinyl sulfones and sodium azide under ambient conditions, Chin. J. Chem.,30, 2786-2790, 2012.

16. Liu Y., Du Q., Yang B., Zhang F., Chu C. * and Liang X., Silica based click amino stationary phase for ion chromatography and hydrophilic interaction liquid chromatography,Analyst,137, 1624-1628，2012.

17. Guo H., Liu R., Yang J., Yang B., Liang X. and Chu C. *, A novel click lysine zwitterionic stationary phase for hydrophilic interaction liquid chromatography, Journal of Chromatography A, 1223，47-52, 2012.

18. Guo H., Chu C. *, Li Y., Liang X. and Yang B. *, A novel silica based click lysine anion exchanger for ion exchange chromatography, Analyst, 136 (24), 5302-5307，2011.

19. 肖玮瑢，薛梅云，郭宏越，刘仁华，梁鑫淼，褚长虎*, 苯甘氨酸肽固定相制备及其色谱性能评价，华东理工大学学报，37（4），464-469，2011.

20. Lu Q, Liao N, Chu C, Shen J, Liu Y, Tao J, Liang X, Liu R, Dioxygen in combination with hydrazine: A practical system for degradation of a broad spectrum of toxic organics in water, J Hazard Mater.,192(3),1186-1191, 2011

21. Huang H.，Guo H., Xue M., Liu Y., Yang J., Liang X. and Chu C. *， Click novel glycosyl amino acid hydrophilic interaction chromatography stationary phase and its application in enrichment of glycopeptides, Talanta, 85, 1642-1647, 2011.

22. Chu C.* and Liu R., Application of click chemistry on preparation of separation materials for liquid chromatography, Chem. Soc. Rev., 40,2177-2188, 2011.

23. Chu C. and Liu R.*, Chloralkanes as chlorinating agents: An efficient approach to acyl chlorides and destruction of chlorinated hydrocarbons,  Appl. Catal. B,101, 343–347, 2011.

24. Tao J., Lu Q., Chu C.*, Liu R.* and Liang X.*, A 4-MeO-TEMPO, PEG-NO₂ and HCl Catalytic System for Highly Efficient Aerobic Oxidation of Alcohols, synthesis，23， 3974-3976，2010.

25. Yin W., Chu C., Lu Q., Tao J., Liang X.* and Liu R.*, Iron Chloride/4-Acetamido-TEMPO/Sodium Nitrite Catalyzed Aerobic Oxidation of Primary Alcohols to the Aldehydes,Advanced Synthesis & Catalysis, 352, 113-118, 2010.

26. Huang H, Jin Y, Xue M, Yu L, Fu Q, Ke Y, Chu C.* and Liang X.*, A novel click chitooligosaccharide for hydrophilic interaction liquid chromatography,Chem. Commun., 6973-6975, 2009.

27. Xue M., Huang H., Ke Y., Chu C.*, Jin Y*. and Liang X.., “Click dipeptide”: A novel stationary phase applied in two dimensional liquid chromatography,Journal of Chromatography A, 1216，8623-8629, 2009.

Patents :

1. 褚长虎，殷伟，柴惠惠，程玲平，郭瑞强，刘仁华，氨基二酸亲水色谱固定相及其制备方法，发明专利：CN 104324707 A

2. 褚长虎，殷伟，郭瑞强，李妍哲，朱传雷，盛哲，氨基二醇亲水色谱固定相及其制备方法，发明专利：CN 104826618 A （授权）

3. 梁鑫淼, 薛梅云, 黄洪雪, 褚长虎: 寡肽反相色谱固定相及其制备方法. 专利申请号: CN 200910197313.X，（2010）（授权）

4. 梁鑫淼, 黄洪雪, 薛梅云, 褚长虎: 壳寡糖亲水色谱固定相及其制备方法. 专利申请号: CN 200910197312.5（2010）

5. 褚长虎, 刘仁华: 利用环境污染物四氯化碳将羧酸氯化为相应酰氯的方法.专利申请号: CN 201010281294.1（2011）

6. 褚长虎，赵谦：利用重排反应制备4-联苯乙酸的方法。专利申请号: CN 201110327861.7（2012）